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Title:
Irregular Sleep-Wake Disorder
Author(s):
SphynxCatVP

Patients with Irregular Sleep-Wake Pattern will usually have a typical average sleep time within a 24 hour period, but it will be broken up into three or more shorter blocks of sleep time in each 24hr time period. This article will go into the differences between this and other circadian rhythm disorders.

WHAT IS IRREGULAR SLEEP-WAKE DISORDER?

Unlike patients with Advanced Sleep Phase, Delayed Sleep Phase, and Non-24 Sleep-Wake Syndrome, a sleep log kept by patients will show no recognizable patterns of sleep or wake times. Instead, sleep will be broken up into multiple shorter blocks in each 24-hr time period, with great unpredictability in sleep-wake timing.

WHAT ARE THE SYMPTOMS?

Page 127 of the ICSD 2001 states:

A. The patient has a complaint of either insomnia or excessive sleepiness.

B. The patient has an irregular pattern of at least three sleep episodes during a 24-hour period.

C. The sleep pattern has been present for at least three months.

D. Total average sleep time per 24-hour period is normal for age.

E. Disturbed chronobiologic rhythmicity is demonstrated by either of the following:
E-1. Continuous polysomnographic monitoring for at least 24 hours shows a loss of the normal sleep-wake pattern
E-2. Continuous temperature monitoring for at least 24 hours shows a loss of the normal temperature

F. No medical or mental disorder accounts for the symptom.

G. The symptoms do not meet the criteria for any other sleep disorder causing insomnia or excessive sleepiness.

Minimal Criteria: A plus B plus C, OR, B plus E.

Severity is graded on the respective amount of insomnia or excessive sleepiness; higher severity with more insomnia/sleepiness.

HOW IS IT DIAGNOSED?

As with any really unusual medical condition, the hardest part is often getting a doctor to take you seriously in the first place!

Generally the patient will be first advised to maintain a log of their wake/sleep times. This will be the fastest way to see what your sleep patterns are like, see if you're getting a decent sleep in any sleep interval, and if any predisposing factors are at work.

Predisposing factors include: work schedule, pain levels, depression, excessive time spent in bed (voluntarily or involuntarily), anemia (which can leave a patient tired all the time if it progresses far enough), sleep apnea, restless limbs during sleep, and so on. While most cases of Irregular Sleep-Wake tend to be due to a brain dysfunction, it's important to rule out any treatable or simple cause first!

A sleep study up to three days in length may be required (to monitor all wake/sleep periods) if there is a need to rule out other sleep disorders - this can be done in a lab, or at home with a small device usually worn on the wrist called an "Actigraph".

Brain imaging tests may show the presence of a physical brain abnormality that is contributing to the sleep problem.

HOW IS IT TREATED?

Treatment for irregular sleep-wake rhythm is aimed at trying to increase stimulation to reset the sleep clock in the brain. The goal is to have one long sleep time at night and one long awake time during the day.

Bright Light Therapy
This works by increasing the amount of natural sun exposure - or it's equivalent - during the day, and avoiding it during the evening and night. Specially designed "daylight bulbs" may be more useful to some if sun exposure isn't practical. These daylight bulbs can be acquired in various forms, such as a light box, a desk lamp, and even a visor that you wear.

Improving Sleep Hygiene
Various sleep hygiene improvements will be suggested such as maintaining a regular sleep schedule - even on weekends, encouraging evening activities that will help the patient stay awake until the desired sleep time, and making the sleep environment more comfortable.

Other methods
Melatonin, sleep aids, wake aids, vitamin B12, and other medications and supplements may be used in an attempt to reset the sleep clock and keep it that way. Physical activity is encouraged duirng the day, and minimal noise and activity at night.

~SphynxCatVP, September 2010


This site contains articles on various medical topics; however, no warranty whatsoever is made that any of the articles are accurate - and even if a statement made about medical matters is accurate, it may not apply to you or your symptoms. These medical articles are provided on a general informational basis only - nothing on this site should be construed as an attempt to offer or render a medical opinion or otherwise engage in the practice of medicine.

Even though the authors may be capable of doing extensive research, it must be understood that neither SphynxCatVP, nor the rest of the contributors, are doctors, despite the presence of any books of the medical profession in the personal libraries of any of the authors. Any such articles are thusly written, in part or in whole, by nonprofessionals. Consequently, there is absolutely no guarantee that any statement contained or cited in an article touching on medical matters is true, precise, or up-to-date.

At best, you can use the article to strike up a conversation with your doctor or other medical professional ABOUT your symptoms, and share any concerns you may have for them to investigate. The medical information provided by this site is of a general nature and CANNOT legally be considered a substitute for the advice of a medical professional.


Credits/References:
American Sleep Association: Irregular Sleep-Wake Rhythm
Ann Acad Med Singapore 2008 Aug;37(8):669-76: Treatment....with Light PDF
PubMed: The Impact of Short, Irregular Sleep Opportunities
Sleep. 2007 November: Circadian Rhythm Sleep Disorders: Part II PDF
Sleep Med Clin. 2009 June: Circadian Rhythm Sleep Disorder PDF
Sleep Medicine Clinics 2009 Feb: Circadian Rhythm Sleep Disorder: ISWR PDF
UM Medical Center: Irregular Sleep-Wake Syndrome Overview
Contact Author(s):
SphynxCatVP          

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